Sign up & Download
Sign in

Sevoflurane with or without antiemetic prophylaxis of dexamethasone in spontaneously breathing patients undergoing outpatient anorectal surgery.

by Jyh-I Wu, Shao-Fong Lu, Yuan-Yi Chia, Lin-Cheng Yang, Wen-Po Fong, Ping-Heng Tan
Journal of clinical anesthesia ()


STUDY OBJECTIVE: To evaluate the prophylactic use of dexamethasone with sevoflurane in outpatient anorectal surgery.\n\nDESIGN: Randomized, controlled study.\n\nSETTING: Operating room and Postanesthesia Care Unit of a general hospital.\n\nPATIENTS: 60 adult, ASA physical status I and II outpatients undergoing anorectal surgery.\n\nINTERVENTIONS: Patients were randomized to receive either dexamethasone 5 mg intravenously (IV; Group D; n = 30) or an equal volume of saline (Group S; n = 30) before anesthesia induction. Anesthesia was induced with propofol 2.5, fentanyl two, and 2% lidocaine one followed by placement of a Laryngeal Mask Airway.\n\nMEASUREMENTS: Frequency of postoperative nausea and vomiting (PONV), visual analog scale (VAS) pain scores, and patient satisfaction were recorded.\n\nMAIN RESULTS: Frequency of PONV and VAS pain scores were significantly lower in Group D than Group S (P < 0.05). The time required for "home readiness" was significantly shorter in Group D than Group S (P < 0.05).\n\nCONCLUSIONS: The prophylactic administration of 5 mg dexamethasone IV can reduce the frequency of PONV, lower VAS pain scores, facilitate recovery to home readiness, and improve satisfaction in outpatients undergoing anorectal surgery.

Cite this document (BETA)

Page 1
Page 2

Readership Statistics

5 Readers on Mendeley
by Discipline
by Academic Status
20% Student (Postgraduate)
20% Researcher (at an Academic Institution)
20% Post Doc
by Country
20% United States
20% Canada

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in