Xenopus egg extracts have distinct Cdk-active and Cdk-inactive states at intermediate cyclin concentrations, a phenomenon known as bistability. A new study shows that this behavior is important for robust cell cycling.
Ingolia, N. (2005, December 6). Cell cycle: Bistability is needed for robust cycling. Current Biology. https://doi.org/10.1016/j.cub.2005.11.012