Superoxide dismutase inhibits the superoxide-driven Fenton reaction at two different levels. Implications for a wider protective role

97Citations
Citations of this article
23Readers
Mendeley users who have this article in their library.

Abstract

Superoxide dismutase (SOD) completely inhibits the damage caused by a ferric-EDTA chelate in the presence of a superoxide-generating system. In this reaction Superoxide is enzymically dismuted to hydrogen peroxide. Since hydrogen peroxide and a ferric-EDTA chelate are themselves a hydroxyl radical-generating system, it follows that SOD must also protect against damage done by this reaction. The ability of SOD to inhibit damage to deoxyribose caused by hydrogen peroxide and a ferric-EDTA chelate is experimentally demonstrated in this paper. © 1985.

Cite

CITATION STYLE

APA

Gutteridge, J. M. C. (1985). Superoxide dismutase inhibits the superoxide-driven Fenton reaction at two different levels. Implications for a wider protective role. FEBS Letters, 185(1), 19–23. https://doi.org/10.1016/0014-5793(85)80732-8

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free