A possible mechanism for concentrating sodium and potassium in the cell nucleus

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Abstract

A dynamic, nonequilibrium mechanism is proposed for concentrating both Na+ and K+ in the cell nucleus. The model is consistent with experiment observations and with known properties of cell membranes. This model could explaing the high nucleoplasm to cytoplasm ratios of Na+ and/or K+ reported for liver kidney, thymus, frog skin, ascites cells, and amphibian oocytes. © 1976, The Biophysical Society. All rights reserved.

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Moore, R. D., & Morrill, G. A. (1976). A possible mechanism for concentrating sodium and potassium in the cell nucleus. Biophysical Journal, 16(5), 527–533. https://doi.org/10.1016/S0006-3495(76)85707-4

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