Myoepithelial crowd control of cancer cells

Abstract

Smooth muscle–like cells can actively remodel epithelia, a mechanism common across developing tissues. In this issue, new work from Sirka et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201802144) demonstrates a novel mechanism for tumor suppression by smooth muscle–like myoepithelial cells of the mammary gland.