Abstract
We report the case of a patient with severe partial epilepsy associated with a focal rolandic, pathologically proven, cortical dysplasia. By measuring intracellular calcium concentrations, functional antiglial non-glutamate receptor 3 (GluR3) autoantibodies were identified in the serum of this pateint. Antineuronal autoantibodies, which interfere with GIuR3-receptor function, also were detected. This observation provides new clues about the involvement of immunologic mechanisms in epileptic disorders. © 2005 by the International League Against Epilepsy.
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Roubertie, A., Boukhaddaoui, H., Sieso, V., De Saint-Martin, A., Lellouch-Tubiana, A., Hirsch, E., … Valmier, J. (2005). Antiglial cell autoantibodies and childhood epilepsy: A case report. Epilepsia, 46(8), 1308–1312. https://doi.org/10.1111/j.1528-1167.2005.53004.x
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