Objectives: To evaluate the efficacy of treatment of drooling by ultrasound-guided botulinum toxin injection of the salivary glands and to determine the optimal modalities of this procedure. Patients and methods: This study is a retrospective review of patients treated for drooling by injection of 100 units of Botox® into the parotid and submaxillary glands between 2002 and 2008. Efficacy was evaluated by a quality of life questionnaire six weeks after the injections. Results: One hundred and eleven injection sessions were performed in 70 patients aged one to 84 years with a beneficial effect in 66% of cases. The most effective protocol was injection of 20 units of botulinum toxin into each submaxillary gland and 30 units of toxin into each parotid gland. Conclusion: The treatment of drooling by Botox® injections into salivary glands is effective. The authors propose ultrasound-guided injection of both submaxillary glands and both parotid glands. These injections can be repeated in the case of recurrence of drooling. © 2011 Elsevier Masson SAS.
Breheret, R., Bizon, A., Jeufroy, C., & Laccourreye, L. (2011). Ultrasound-guided botulinum toxin injections for treatment of drooling. European Annals of Otorhinolaryngology, Head and Neck Diseases, 128(5), 224–229. https://doi.org/10.1016/j.anorl.2010.12.010