Transcranial Doppler After Successful Endovascular Revascularization and Hospitalization Outcomes

Abstract

BACKGROUND: Almost half of large-vessel occlusion strokes have unfavorable outcomes despite successful endovascular therapy. We aim to investigate whether postrevascularization cerebral hemodynamics, determined by transcranial Doppler (TCD), associate with hospitalization outcomes in this population. METHODS: The current observational cohort study analyzed 155 patients with successfully revascularized anterior circulation large-vessel occlusion stroke (mean age, 68.3 +/- 15.4 years; 55% women) who had TCD within 48 hours from endovascular therapy. TCD parameters (mean flow velocity, peak systolic velocity, and pulsatility index) were recorded at the ipsilateral middle cerebral artery, and blood flow signals were categorized using the Thrombolysis in Brain Ischemia grades into normal (grade 5), stenotic (grade 4), or dampened (grade