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Acne vulgaris is a common skin condition, one that is associated with significant psychological disability. The psychological impairments in acne include higher rates of depression, anxiety, anger and suicidal thoughts. Despite a paucity of clinical research, patients with skin conditions and/or mental health disorders are frequent consumers of dietary supplements. An overlap may exist between nutrients that potentially have both anti-acne and mood regulating properties; examples include omega-3 fatty acids from fish oil, chromium, zinc and selenium. Here we report on five cases of acne treated with eicosapentaenoic acid and antioxidant nutrients. Self-administration of these nutrients may have improved inflammatory acne lesions and global aspects of well-being; the observations suggest a need for controlled trials. © 2008 Rubin et al; licensee BioMed Central Ltd.
Rubin, M. G., Kim, K., & Logan, A. C. (2008). Acne vulgaris, mental health and omega-3 fatty acids: A report of cases. Lipids in Health and Disease, 7. https://doi.org/10.1186/1476-511X-7-36