In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue. © 2011 by the authors; licensee MDPI, Basel, Switzerland.
Frey, S. K., & Vogel, S. (2011). Vitamin A metabolism and adipose tissue biology. Nutrients. MDPI AG. https://doi.org/10.3390/nu3010027