The identification of Drosophila genes that inhibit proliferation while simultaneously promoting apoptosis - decreasing cell number - or that promote proliferation while simultaneously inhibiting apoptosis -increasing cell number - has revealed new ways that cell birth and death may be coupled to meet the needs of development.
Jaklevic, B., & Su, T. T. (2003). Cell Turnover: Flexible Coupling Meets the Needs of Development. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2003.09.050