To assess the efficacy of continuous extrapleural intercostal nerve block (CEINB) with 0.5% bupivacaine on postoperative pain, pulmonary function and pulmonary complications, a prospective, randomised, double blind controlled trial was conducted on comparable patients under going lungresections; n = 21 (control), n = 25 (bupivacaine). The bupivacaine group required less papaveretum in the first 24 h (P < 0.01) and had lower pain scores over 5 postoperative days (P < 0.01). Pulmonary function recovered earlier in the bupivacaine group. Pulmonary complications occurred in 1 patient with normal lung function and 12 patients with obstructive airways disease (COAD): FEV1/FVC < 70%. There were no infusion-related complications. CEINB has been shown to be safe and effective in reducing postoperative pain and pulmonary complications. CEINB minimises the loss of lung function after thoracotomy and restores impaired pulmonary mechanics more rapidly. © Springer-Verlag.
Berrisford, R. G., Sabanathan, S. S., Mearns, A. J., & Bickford-Smith, P. J. (1990). Pulmonary complications after lung resection: The effect of continuous extrapleural intercostal nerve block. European Journal of Cardio-Thoracic Surgery, 4(8), 407–410. https://doi.org/10.1016/1010-7940(90)90068-B