Marine Sterols: XXI: Isolation of (245')-3/j-hydroxyergost-5-en-21-oic Acid From A Sclerophytum Sp: Of Soft Coral

Abstract

The lipid extract of the Sclerophytum sp. of soft coral, collected off the coast of the Andaman and Nicobar Islands, afforded a new sterol la. The structure of la was shown to be (24S)-3/l-hydroxyergost-5-en-21-oic acid, the first member of a class of marine sterols having a C-21 carboxylic acid, by spectral analyses and conversion to (245)-ergostane. © 1992, The Pharmaceutical Society of Japan. All rights reserved.