Pomegranate extracts in the management of men's urologic health: Scientific rationale and preclinical and clinical data

11Citations
Citations of this article
46Readers
Mendeley users who have this article in their library.

Abstract

Multiple strands of research provide growing evidence that diet, nutrition, and life style play a role in the development and the course of urological diseases. Numerous micronutrients and polyphenols found in soy, green tea, and many fruits and vegetables have been described to impact diseases including erectile dysfunction, benign prostatic hyperplasia, and prostate cancer. However, oftentimes these reports lack both a scientific rationale and supportive evidence base. The efficacy of pomegranate, on the other hand, in the modulation of central biological processes like inflammation, hypoxia, and oxidative stress that are important in the pathogenesis of urological maladies has been robustly demonstrated in preclinical in vitro and in vivo studies. Moreover, clinical trials have further supported its use in the treatment of several diseases, in particular in the management of prostate cancer. Herein, we critically review the scientific knowledge about the current role and future prospects for the use of pomegranate extracts in the therapy of erectile dysfunction, benign prostatic hyperplasia, and prostate cancer. © 2013 Kroeger N. et al.

Cite

CITATION STYLE

APA

Kroeger, N., Belldegrun, A. S., & Pantuck, A. J. (2013). Pomegranate extracts in the management of men’s urologic health: Scientific rationale and preclinical and clinical data. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2013/701434

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free