The evidence clearly supports the superiority of parenteral artesunate over quinine for the treatment of severe malaria in both adults and children and in different regions of the world.
Sinclair, D., Donegan, S., Isba, R., & Lalloo, D. G. (2012). Artesunate versus quinine for treating severe malaria. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd005967.pub4