Pulmonary Mycobacterium kansasii Infection Mimicking Malignancy on the 18 F-FDG PET Scan in a Patient Receiving Etanercept: A Case Report and Literature Review

  • Min Z
  • Amlani M
N/ACitations
Citations of this article
11Readers
Mendeley users who have this article in their library.

Abstract

A 66-year-old male presented with chest pain, malaise, generalized weakness, and weight loss. He had been receiving etanercept injection for rheumatoid arthritis. Chest X-ray revealed a right upper lobe mass. Chest computed tomography (CT) showed a right apical mass, highly suggestive of a Pancoast tumor. The thoracic fluorine-18 fluoro-deoxy-glucose ( 18 F-FDG) positron emission tomography (PET) scan demonstrated significantly high metabolic pulmonary lesions with the standardized uptake value (SUV) of 12.5, consistent with lung cancer. The patient underwent bronchoscopy and bronchoalveolar lavage (BAL). BAL cytology was negative for malignant cells. BAL acid fast bacilli (AFB) smears were positive, and Mycobacterium kansasii was eventually isolated. He received a 12-month course of rifampin, isoniazid, and ethambutol. Interval resolution of pulmonary lesions was noted on follow-up serial CT chest studies. There has been increasing incidence of nontuberculous mycobacterial infections reported in patients treated with the antitumor necrosis factor-alpha (anti-TNF-alpha) agents. Infectious foci have an increased glucose metabolism which potentially causes a high FDG uptake on the 18 F-FDG PET scan, leading to undue anxiety and cost to the patients. This is the first reported case of pulmonary M. kansasii infection with a positive thoracic 18 F-FDG PET study mimicking malignancy in a patient on etanercept.

Cite

CITATION STYLE

APA

Min, Z., & Amlani, M. (2014). Pulmonary Mycobacterium kansasii Infection Mimicking Malignancy on the 18 F-FDG PET Scan in a Patient Receiving Etanercept: A Case Report and Literature Review . Case Reports in Pulmonology, 2014, 1–5. https://doi.org/10.1155/2014/973573

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free