Adipose tissue plays essential roles in various aspects of skin physiology, from regulating hair follicle morphogenesis to wound healing. Peroxisome proliferator-activated receptor gamma is important for the maintenance of adipose tissue and has been implicated in some types of hair loss; however, its function during the hair cycle is still unclear. Sardella et al. investigate the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel global peroxisome proliferator-activated receptor gamma-null mouse.
Islam, N., & Garza, L. A. (2018, March 1). Adipose and Hair Function: An aPPARent Connection. Journal of Investigative Dermatology. Elsevier B.V. https://doi.org/10.1016/j.jid.2017.10.019