Abstract
A family (H J pedigree) segregating for the A and F alleles at cholinesterase locus 1 is described. Several members of this family have extremely high serum cholinesterase levels. Apparent anomalous results led to the recognition of a new allele E1(superior j) also segregating in the family. The data are consistent with the hypothesis that the E1(superior j) causes reduction of 'usual' (E1(superior u)) molecules by about 66%. Whether this is because of retarded synthesis or accelerated degradation of serum cholinesterase remains to be determined.
Cite
CITATION STYLE
Garry, P. J., Dietz, A. A., Lubrano, T., Ford, P. C., James, K., & Rubinstein, H. M. (1976). New allele at cholinesterase locus 1. Journal of Medical Genetics, 13(1), 38–42. https://doi.org/10.1136/jmg.13.1.38
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