Degeneracy of the genetic code and stability of the base pair at the second position of the anticodon

Abstract

With an analysis of the structural constraints of the anticodon-codon interaction within the decoding center of the ribosome, we show that the extent of degeneracy at the third position of the anticodon is determined by the level of stability of the base pair at the second position. Published by Cold Spring Harbor Laboratory Press. Copyright © 2008 RNA Society.