The role of double-stranded break repair in the creation of phenotypic diversity at cereal VRN1 loci

Abstract

Nonhomologous repair of double-stranded breaks, although fundamental to the maintenance of genomic integrity in all eukaryotes, has received little attention as to its evolutionary consequences in the generation and selection of phenotypic diversity. Here we document the role of illegitimate recombination in the creation of novel alleles in VRN1 orthologs selected to confer adaptation to annual cropping systems in barley and wheat. Copyright © 2007 by the Genetics Society of America.