The relationship between patient-related factors and medication adherence among Nigerian patients taking highly active anti-retroviral therapy

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Abstract

Background: Through several initiatives, there are increasingly more people who have access to anti-retroviral therapy. Adherence to therapy is, however,necessary for successful management of disease. Objectives: The objectives of this study were to describe adherence rates and determine what patient-related factors are related to adherence to anti-retroviral therapy among adult patients in an HIV clinic located in Lagos, Nigeria. Methods: Adherence was measured using the two-week self-recall method. Barriers, satisfaction with therapy, and socio-demographic and clinical variables served as independent variables. Data were collected via self-administered surveys. Results:. Most of the patients (79.5%) reported 100% adherence. The significant (p<0.05) barriers to adherence were forgetfulness, running out of medication, alcohol use, and medication side effects. For every unit increase in the number of barriers, patients were 60.8% less likely to be 100% adherent (p <0.05, odds ratio, OR = 0.392,95% CI = 0.295-0.523). Conclusion: Interventions should target helping patients cope with forgetfulness, specifically employing strategies to overcome busyness in schedules, being away from home, and tiredness.

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APA

Nduaguba, S. O., Soremekun, R. O., Olugbake, O. A., & Barner, J. C. (2017). The relationship between patient-related factors and medication adherence among Nigerian patients taking highly active anti-retroviral therapy. African Health Sciences, 17(3), 738–745. https://doi.org/10.4314/ahs.v17i3.16

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