Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor β (ERβ) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERβ would have prognostic or therapeutic value. © 2010 Elsevier Inc. All rights reserved.
Loda, M., & Kaelin, W. G. (2010, April 13). Prostate Cancer: Beta Control Your Hormones. Cancer Cell. https://doi.org/10.1016/j.ccr.2010.03.013