ArticleOPEN ACCESS

The enemy of my enemy: PTEN and PLCXD collude to fight endosomal PtdIns(4,5)P2

Journal of Cell Biology
DOI: 10.1083/JCB.201906022
0Citations
Citations of this article
11Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Loss of the phosphoinositide 5-phosphatase OCRL causes accumulation of PtdIns(4,5)P2 on membranes and, ultimately, Lowe syndrome. In this issue, Mondin et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201805155) discover that a surprising partnership between PTEN and the phospholipase PLCXD can compensate for OCRL to suppress endosomal PtdIns(4,5)P2 accumulation.

Cite

CITATION STYLE

APA

Del Signore, S. J., & Rodal, A. A. (2019, July 1). The enemy of my enemy: PTEN and PLCXD collude to fight endosomal PtdIns(4,5)P2. Journal of Cell Biology. Rockefeller University Press. https://doi.org/10.1083/JCB.201906022

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free