Antibacterial and immunomodulatory effect of cell free supernatant of Lactobacillus plantarum against Shigella flexneri

Abstract

Background & Objectives: Shigellosis is endemic throughout the world causing great deal of morbidity and mortality. Emergence of antibiotic resistance and lack of vaccine against Shigella, necessitates exploitation of alternative strategies to combat Shigella infection. The present study was undertaken to evaluate the effect of cell free supernatant (CFS) from Lactobacillus plantarum (L. plantarum) against Shigella flexneri (S. flexneri).