Papillomavirus DNA replication - From initiation to genomic instability

Citations of this article
Mendeley users who have this article in their library.


Papillomaviruses establish their productive life cycle in stratified epithelium or mucosa, where the undifferentiated proliferating keratinocytes are the initial targets for the productive viral infection. Papillomaviruses have evolved mechanisms to adapt to the normal cellular growth control pathways and to adjust their DNA replication and maintenance cycle to contend with the cellular differentiation. We provide overview of the papillomavirus DNA replication in the differentiating epithelium and describe the molecular interactions important for viral DNA replication on all steps of the viral life cycle. © 2008 Elsevier Inc. All rights reserved.




Kadaja, M., Silla, T., Ustav, E., & Ustav, M. (2009, February 20). Papillomavirus DNA replication - From initiation to genomic instability. Virology.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free