Alkaloids from fissistigma latifolium (Dunal) merr.

Abstract

A phytochemical study of the bark of Fissistigma latifolium (Annonaceae) yielded a new aporphine alkaloid, (-)-N-methylguattescidine (1), and eight known alkaloids: liriodenine (2), oxoxylopine (3), (-)-asimilobine (4), dimethyltryptamine (5), (-)- remerine (6), (-)-anonaine (7), columbamine (8) and lysicamine (9). The compounds were isolated using various chromatographic methods and structural elucidation was accomplished by means of spectroscopic methods, notably 1D-NMR ( 1H, 13C, DEPT), 2DNMR (COSY, HMQC, HMBC), UV, IR and MS. © 2010 by the authors; licensee MDPI, Basel, Switzerland.