In this issue of Developmental Cell, Aram et al. (2016) identify a mechanism that uses a Krebs cycle protein to control local activation of a ubiquitin ligase complex at the mitochondrial outer membrane for temporally and spatially restricted caspase activation during Drosophila sperm differentiation.
Minis, A., & Steller, H. (2016, April 4). Krebs Cycle Moonlights in Caspase Regulation. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2016.03.016