Background: Dengue infection is amajor public health problem in Vietnam where high incidence and repeated large outbreaks are reported . The knowledge on dengue cost of illness is limited in Vietnam; while, the private demand for future dengue vaccines is not studied which are essential for decision making on dengue prevention, control and introduction of future vaccines. Methods: We are conducting a comprehensive economic study composed of a set of three surveys for estimating cost-of-illness (COI); healthcare utilization; and willingness-to-pay (WTP) for future dengue vaccine in Nha Trang, Vietnam. The COI study will estimate cost of treating 200 confirmed dengue cases which includes direct costs for medicines, diagnostics, health service delivery, and transport; as well as indirect cost due to productivity loss among patients and care takers. A questionnaire will be administered to 400 participants to estimate private willingness to pay for hypothetical vaccines against dengue infection where they will be oriented about future dengue vaccine, presented with one of five randomly assigned prices and asked how many vaccines they would purchase for the household and who would receive the vaccine. A questionnaire will be used for assessing health seeking behavior of the population for dengue cases. Results: The COI survey was launched in Khanh Hoa General Hospital (KHGH) in Nha Trang on the 1st of Nov., 2011 and a total of 13 dengue-confirmed hospitalized patients and 2 outpatients have been recruited thus far. Preliminary analysis showed that the private direct out-of-pocket cost per hospitalized dengue case is fairly high in Nha Trang (VND 2.5 million; US$125). Cost of illness can be estimated once more cases are recruited. Focus group discussions and a pilot test (44 household interviews) were conducted prior to WTP survey. Most respondents (82%) understood about proposed future dengue vaccine. Price points in the questionnaire were determined based on the pilot test and questionnaire is being finalized. Conclusion: Once the sample size is achieved, we will calculate direct and indirect cost-of-illness of the dengue-confirmed cases that sought care at the facility. Affordable vaccine price for public and privatedemandfor up-coming dengue vaccine will be assessed.
Mogasale, V., Maskery, B., Lim, J., Thiem, V. D., Tho, L. H., Anh, D. D., & Da Silva, L. (2012). Economic evidence for policy makers in Vietnam: dengue fever economic burden of disease and household willingness to pay for dengue vaccines. International Journal of Infectious Diseases, 16, e310. https://doi.org/10.1016/j.ijid.2012.05.1005