It is widely accepted that bacteriorhodopsin undergoes global conformational changes during its photocycle. In this review, the structural properties of the M and N intermediates are described in detail. Based on the clarified global conformational change, we propose a model for the molecular mechanism of the proton pump. The global structural change is suggested to be a key component in establishing vectorial proton transport. (C) 2000 Elsevier Science B.V.
Kataoka, M., & Kamikubo, H. (2000, August 30). Structures of photointermediates and their implications for the proton pump mechanism. Biochimica et Biophysica Acta - Bioenergetics. https://doi.org/10.1016/S0005-2728(00)00137-7