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Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress. © 2012 Souza et al.; licensee BioMed Central Ltd.
Sousa, G. T., Lira, F. S., Rosa, J. C., De Oliveira, E. P., Oyama, L. M., Santos, R. V., & Pimentel, G. D. (2012). Dietary whey protein lessens several risk factors for metabolic diseases: A review. Lipids in Health and Disease. https://doi.org/10.1186/1476-511X-11-67