The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.
CITATION STYLE
Kavanaugh, M. P., Wang, H., Boyd, C. A., North, R. A., & Kabat, D. (1994). Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter. Archives of Virology. Supplementum. https://doi.org/10.1007/978-3-7091-9326-6_47
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