Abstract
The four-component reaction of cyclobutanone, dibenzylamine and (isocyanoimino)triphenylphosphorane in the presence of aromatic carboxylic acids proceeds smoothly at room temperature under neutral conditions to afford N,N-dibenzyl-1-(5-aryl-1,3,4-oxadiazol-2-yl)cyclobutylamine derivatives in high yields. © 2012 Copyright (CC) SCS.
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Shajari, N., Kazemizadeh, A. R., & Ramazani, A. (2012). Efficient one-pot, four-component synthesis of N,N-dibenzyl-1-(5-aryl-1,3, 4-oxadiazol-2-yl)cyclobutylamine derivatives from the reaction of (isocyanoimino)triphenylphosphorane, dibenzylamine, an aromatic carboxylic acid and cyclobutanone. Journal of the Serbian Chemical Society, 77(9), 1175–1180. https://doi.org/10.2298/JSC111014024S
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