Effect of Magnesium Oxide on Physical and Biological Properties in β-tricalcium Phosphate Ceramic

Abstract

β-TCP is bioresorbable ceramic which has excellent osteoinduction and osteoconduction properties for using as bone cement and bone implant material. However, their natural brittleness and insufficient compaction after sintering under the transformation phase from β- to α-TCP limit their utility for clinical performance. The purpose of this work is to investigate the effect of magnesium ion as the doping element on the β-TCP. The experiment was conducted by introduced 1.0wt% of MgO into the β-TCP structure via simultaneous balls milling and mixing method. Afterward, the powders were pressed into pellets and went through conventional sintering method. The sintered samples were examined by powder X-ray diffraction (XRD), density and biological test for investigation.