Alice in Wonderland Syndrome: Case Report

  • H B
  • M G
  • FA E
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Objective: Alice in Wonderland syndrome (AIWS), named after a novel that was written by Lewis Carroll, was first reported in 1955 by J. Todd. We herein report a case of AIWS following a cerebral infarction. Patients: A 61-year-old right-handed male developed a cerebral infarction and was admitted to the hospital. He was transferred to our hospital for rehabilitation on the 19th day after the stroke. A neurological examination performed on admission revealed no abnormalities, except for mild impairment of the two-point discrimination on the right side and a mild motor aphasia. On admission he complained of a bizarre sensation in his right extremity, which he described as feeling that his right extremity length was half that of the left extremity. He was distressed by this bizarre feeling throughout the day, particularly due to a fear of falling down the stairs. The sense of a short extremity disappeared when he looked at his right limb visually. He felt that the weight of his right extremity was lighter than that of the left extremity and stated that the objects grasped tactually in his right hand were lighter in weight and smaller in size than those grasped in the left hand. No prosopagnosia or autotopagnosia were observed. MRI and SPECT images revealed broad hypoperfusion in the left hemisphere. Discussion and conclusions: The bizarre sensation in the patient's extremity was considered to be consistent with a microsomatognosia, as part of a cluster of symptoms called AIWS. The occurrence of AIWS in stroke patient is extremely rare.




H, B., M, G., & FA, E. (2018). Alice in Wonderland Syndrome: Case Report. Journal of Neuroscience and Neuropsychology, 2(1), 1–2.

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