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A bicyclic diterpenoid with a new 15,16-dinorlabdane carbon skeleton from leonurus japonicus and its coagulant bioactivity

Molecules (2013) 18(11) 13904-13909
DOI: 10.3390/molecules181113904
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Abstract

A new 15,16-dinorlabdane diterpenoid 1 and a known labdane diterpenoid 2, together with three known ergosterols 3-5, were isolated from the EtOAc-soluble portion of the EtOH extract of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. Compound 1 showed in vitro coagulant activity in the APTT, PT, TT, and FIB assays. © 2013 by the authors.

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Peng, F., Xiong, L., & Zhao, X. M. (2013). A bicyclic diterpenoid with a new 15,16-dinorlabdane carbon skeleton from leonurus japonicus and its coagulant bioactivity. Molecules, 18(11), 13904–13909. https://doi.org/10.3390/molecules181113904

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