Palladium catalysts for the Suzuki cross-coupling reaction: An overview of recent advances

Abstract

This review with 206 references covers the literature published until March 2004 on the development and applications of new efficient catalyst systems for the Suzuki palladium-catalysed cross-coupling reaction of organoboron compounds with organic electrophiles. Where possible, the relative advantages of the new catalyst systems in this synthetically very important carbon-carbon bond forming reaction have been compared. 1 Introduction 2 Palladacycle Complexes as Catalyst Precursors 3 Catalyst Systems Composed of Pd(0) or Pd(II) Derivatives and Electron-Rich and/or Bulky Phosphine Ligands 4 Catalyst Systems Composed of Pd(0) or Pd(II) Derivatives and N-Heterocyclic Carbene Ligands 5 Water-Soluble Catalyst Precursors 6 Ligandless Catalyst Precursors 7 Other Novel Pd Catalyst Precursors 8 Conclusions.