Three new antiviral triterpenes from Aster tataricus

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Abstract

Three new shionane-type triterpenes, shion-22-methoxy-20(21)-en-3-one (1), shion-22(30)-en-3,21-dione (2), shion-22-methoxy-20(21)-en-3β-ol (3), were isolated from the rhizomes of Aster tataricus. Their structures have been determined on the basis of MS, IR, 1D and 2D NMR spectral evidences. Compounds 1 and 2 show inhibitory activities on HBsAg with IC50 values of 0.89 and 4.49 μgmL-1, respectively, 1 shows inhibitory activity on HBeAg with an IC50 value of 0.83 μgmL-1, and 2 shows inhibitory activity on HA with an IC50 value of 11.18 μgmL -1. © 2010 Verlag der Zeitschrift für Naturforschung, Tübingen.

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APA

Zhou, W. B., Tao, J. Y., Xu, H. M., Chen, K. L., Zeng, G. Z., Ji, C. J., … Tan, N. H. (2010). Three new antiviral triterpenes from Aster tataricus. Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 65(11), 1393–1396. https://doi.org/10.1515/znb-2010-1116

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