The pangenome: A data-driven discovery in biology

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Abstract

An early example of Big data in biology: how a mathematical model, developed to address a practical question in vaccinology, transformed established concepts, opening biology to the "unbounded."

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Medini, D., Donati, C., Rappuoli, R., & Tettelin, H. (2020). The pangenome: A data-driven discovery in biology. In The Pangenome: Diversity, Dynamics and Evolution of Genomes (pp. 3–20). Springer International Publishing. https://doi.org/10.1007/978-3-030-38281-0_1

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