Synthesis of the Polymethylols of Phenol

Abstract

The compounds, 2,6-dimethylolphenol, 2,4-dimethylolphenol and 2,4,6-trimethylolphenol have been synthesized by means of reduction of corresponding acetoxyphenyl esters with lithium aluminum hydride. The polymethylols of phenol are crystalline compounds of sharp melting point and are easily soluble in water. 2,6-Dimethylolphenol is dimorphic. Preparation of 2,4,6-trimethylolphenol by direct reaction of phenol and formaldehyde is also described. © 1952, American Chemical Society. All rights reserved.