Anti-arthritic Activity of Senna auriculata Leaves Extract on Formaldehyde-Induced Arthritic Rats

Abstract

Since ancient days, herbal medicines are serving humankind. Consequently, most therapeutic agents developed are of plant origin. Senna auriculata is highly valued in Indian drugs for managing painful inflammation and diabetes. This study aimed to measure the anti-inflammatory potential of Senna auriculata leaf extract. The anti-arthritis activity was evaluated using Inhibition % of paw edema, Haemoglobin Estimation, C-reactive protein (CRP) detection, and radiography. The % of inhibition was compared with the standard drug. Phytochemical investigation indicates the presence of various phytoconstituents like alkaloids, flavonoids, tannins, steroids, and Anthraquinone and Saponin Glycosides. Senna auriculata leaves extract inhibition of paw volume and swelling.