Micro-capillary liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry - A powerful tool for peptide and protein identification

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Abstract

In order to be able to study complex biological samples, a micro-capillary liquid chromatography system was coupled to a 9.4 T Fourier transform ion cyclotron resonance mass spectrometer. The setup was tested on a tryptic digest of bovine serum albumin, which resulted in high sequence coverage (> 92 %) of the protein.

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Ramström, M., Palmblad, M., Amirkhani, A., Tsybin, Y. O., Markides, K. E., Håkansson, P., & Bergquist, J. (2001). Micro-capillary liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry - A powerful tool for peptide and protein identification. Acta Biochimica Polonica. Acta Biochimica Polonica. https://doi.org/10.18388/abp.2001_3871

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