A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the μM level against three human tumor cell lines. © 2009 by the authors; licensee Molecular Diversity Preservation International.
Coello, L., Martín, M. J., & Reyes, F. (2009). 1,5-Diazacyclohenicosane, a new cytotoxic metabolite from the marine sponge Mycale sp. Marine Drugs, 7(3), 445–450. https://doi.org/10.3390/md7030445