Highly active killer T cells mediate a stable standoff during controlled persistent infections. In this issue of Immunity, Robey and colleagues describe a unique antigen-addicted T cell population bearing characteristics of both effector and memory CD8+ T cells that provides a continuous supply of potent killer T cells to curb Toxoplasma gondii growth during latency.
Kalia, V., & Sarkar, S. (2016, July 19). Antigen-Addicted T Cell Reserves Trickle Charge the Frontline Killers. Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2016.07.004