A Systematic Review on Cyclodextrin: A Versatile Tool for Enhanced Formulations and Diverse Applications

Abstract

Cyclodextrins (CDs) are cyclic oligosaccharides that have gained significant attention in various industries due to their unique structural properties and versatile applications. This study aims to provide a comprehensive overview of the types, formulation techniques, and wide-ranging applications of cyclodextrins. It explores the formulation techniques used to incorporate cyclodextrins into different matrices. Cyclodextrin Complex Formation, Cyclodextrin-Based Nanostructures involves the encapsulation of guest molecules within the hydrophobic cavity of cyclodextrins. The study presents a broad range of applications where cyclodextrins have demonstrated their utility. The pharmaceutical industry extensively employs cyclodextrins as excipients to enhance drug solubility, stability, bioavailability, and taste masking. Additionally, CDs find applications in the food and beverage industry for flavor encapsulation, preservation, and controlled release of bioactive compounds. They also play a vital role in various fields, including agriculture, cosmetics, environmental remediation, and separation sciences.