Indonesian Medicinal Plants: I: Chemical Structures of Calotroposides A and B, Two New Oxypregnane-Oligoglycosides from the Root of Calotropis gigantea (Asclepiadaceae)

Abstract

Two new oxypregnane-oligoglycosides named calotroposides A (1) and B (2) have been isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant, and their chemical structures have been elucidated by chemical and spectroscopic methods as 12-0-benzoyllineolon 3-0-/l-D-cymaropyranosyl(l-»4)-/?-D-oleandropy-ranosyl (1 -> 4)-/?-D-oleandropyranosy 1 (1 -> 4)-/J-D-cymaropyranosyl (1 -> 4)-/f-D-cymaropyranoside and 12-O-benzoylde-acetylmetaplexigenin 3-0-/J-D-cymaropyranosyl(l->4)-/f-D-oleandropyranosyl(l ->4)-/?-D-oleandropyranosyl(l ->4)-/?-D-cymaropyranosyl(l -> 4)-/J-D-cymaropyranoside, respectively. © 1992, The Pharmaceutical Society of Japan. All rights reserved.