An efficient synthesis of 1-H-pyrazole-4-carboxylic acid esters with Vilsmeier reagent under neat conditions

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Abstract

A convenient, solvent-free Vilsmeier reagent is experimented under neat condition (both thermal and microwave conditions). An efficient method for the synthesis of various substituted 1H-pyrazole-4-carboxylic acid esters is reported.

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Sridhar, R., Sivaprasad, G., & Perumal, P. T. (2004). An efficient synthesis of 1-H-pyrazole-4-carboxylic acid esters with Vilsmeier reagent under neat conditions. Journal of Heterocyclic Chemistry, 41(3), 405–408. https://doi.org/10.1002/jhet.5570410316

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