The Impact of Climate Change on The Bioavailability of Environmental Toxins and Their Toxicological Effects

Abstract

Climate change has become one of the biggest challenges for the 21st century. Global warming, sea level rise, changes in weather conditions, and atmospheric contamination caused by climate change not only have impacts on nature but also present threats to human health. Climate change can influence the generations and distribution of some representative toxic compounds with specific examples, including heavy metals (arsenic and manganese), persistent organic pollutants (POPs), air pollutants, and biotoxins (domoic acid and β-N-methylamino-L-alanine). This review discusses how the effects of climate change drive the production and spread of toxic substances that enter the human body through different means as well as presents the biochemical mechanisms and experimental evidence of their toxicological effect on human health, which provides an insight on climate change allowing toxic substances to enter human body and calls on readers to understand and pay attention to climate change from a more comprehensive aspect