Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety

  • Appelt H
  • Oliveira J
  • Santos R
  • et al.
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Abstract

A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.

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Appelt, H. R., Oliveira, J. S., Santos, R. C. V., Rodrigues, O. E. D., Santos, M. Z., Heck, E. F., & Rosa, L. C. (2013). Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety. International Journal of Carbohydrate Chemistry, 2013, 1–5. https://doi.org/10.1155/2013/320892

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