A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.
CITATION STYLE
Appelt, H. R., Oliveira, J. S., Santos, R. C. V., Rodrigues, O. E. D., Santos, M. Z., Heck, E. F., & Rosa, L. C. (2013). Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety. International Journal of Carbohydrate Chemistry, 2013, 1–5. https://doi.org/10.1155/2013/320892
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