Antifungal activity and phytochemical analysis of Ficus sycomorus leaf extract on malassezia glubosa

Abstract

The Antifungal activity of the aqueous extract of Ficus sycomorus on Malassezia glubosa was carried out at different concentrations to determine its effect on the test isolate. Ficus sycomorus leaves were collected from the farmland at Gidan yamma village in Usmanu Danfodiyo University, Sokoto, Nigeria. The leaves of the plant were air dried under shed and at room temperature for 7days. The plant (leaves) was grinded into fine powdered form using sterilized mortar and pestle. 100g of the powder was weighed and dissolved in 1000ml of distilled water and allowed to soak for 24hrs. It was sieved and the aqueous extract was put in a drying cabinet machine to evaporate the moisture content for 72hrs. The extract was prepared into different concentrations. The concentrations were (10, 20, 40, 60, and 100) mg/ml which was all tested against the test isolates (Malassezia glubosa). The antifungal activity of the aqueous extract of Ficus sycomorus on Malassezia glubosa increases with higher concentration and the highest mean radial growth was (7mm) at 100mg/ml. The phytochemical analysis carried out on the extract showed the presence of Tannins (+++), Saponins (++), Alkaloids (+++), Glycoside (+++), Flavonoids (++). The presences of these compounds have effect on the altering growth of the fungi at increasing concentration.