Circulation of prions within dust on a scrapie affected farm

8Citations
Citations of this article
26Readers
Mendeley users who have this article in their library.

Abstract

Prion diseases are fatal neurological disorders that affect humans and animals. Scrapie of sheep/goats and Chronic Wasting Disease (CWD) of deer/elk are contagious prion diseases where environmental reservoirs have a direct link to the transmission of disease. Using protein misfolding cyclic amplification we demonstrate that scrapie PrP<sup>Sc</sup> can be detected within circulating dusts that are present on a farm that is naturally contaminated with sheep scrapie. The presence of infectious scrapie within airborne dusts may represent a possible route of infection and illustrates the difficulties that may be associated with the effective decontamination of such scrapie affected premises.

Cite

CITATION STYLE

APA

Gough, K. C., Baker, C. A., Simmons, H. A., Hawkins, S. A., & Maddison, B. C. (2015). Circulation of prions within dust on a scrapie affected farm. Veterinary Research, 46(1). https://doi.org/10.1186/s13567-015-0176-1

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free